Abstract
The effect of acute ethanol ingestion on plasma gamma aminobutyric acid (GABA) levels was investigated in eight volunteers. Subjects were studied on two days: a control during which light activity and non-alcoholic fluid intake was allowed and a study day during which ethanol was ingested to maintain blood alcohol levels at a mean of 130 mg%. Plasma GABA levels were estimated at 1, 4 and 8 hr. GABA levels were raised at 1 and 4 hr on the study day compared to the control day. GABA levels at 8 hr were not significantly different on the two days. Acute alcohol ingestion raised plasma GABA in healthy male volunteers.
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