Abstract
Abstract — Aim: To evaluate the acute effects of a resistance exercise session performed on ladder on energy metabolism, stress, and muscle damage in rats. Methods: Male Wistar rats were randomly distributed in Exercise (E) (n=30) and Control (C) (n = 20) groups. The E group performed a resistance exercise session on a vertical ladder with weights on their tails. Blood samples were collected at rest and after each climb to analyze lactate levels and ten minutes after the last climb to analyze lactate dehydrogenase (LDH), creatine kinase (CK), and corticosterone levels. Results: Blood lactate levels remained stable during exercise. Serum corticosterone, blood glucose, LDH and CK levels increased and glycogen content decreased in the E group, when compared to the C group. Conclusion: These results suggest that resistance exercise performed on ladder is a model of high-intensity exercise. However, the stabilization of lactate during the session suggests that the aerobic metabolism is an important factor during the intervals between climbs.Keywords: resistance exercise; metabolism; stress; muscle damage
Highlights
Over the last decade, several studies have described the acute and chronic physiological effects of resistance exercise[1,2]
The enzymes creatine kinase (CK) and lactate dehydrogenase (LDH) are required in the ATP-PCr and in lactate production, respectively, and both are released into the bloodstream when tissue damage occurs[7,8]
Blood lactate levels remained stable during the resistance exercise session in this particular model
Summary
Several studies have described the acute and chronic physiological effects of resistance exercise[1,2]. These findings have established the importance of this modality of exercise to improve physical functioning and quality of life in healthy people[2] or in patients with chronic diseases such as cancer[3] or diabetes[4]. Regarding the acute physiological responses of the resistance exercise, it is well known that, during high-intensity activities, the phosphagen system (ATP-PCr) and anaerobic glycolysis, respectively, are crucial to ATP synthesis and maintenance of exercise intensity. The aerobic system predominates during the interval between sets and exercises, using lipids as main substrate and metabolizing the increased lactate in the heart, liver, and non-working muscles[6]
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