Abstract
BackgroundTo determine the acute effects of ingesting a thermogenic drink (Celsius, Delray Beach, FL) (TD) on changes in metabolism and lipolysis.MethodsHealthy college-aged male (23.2 ± 4.0 y, 177.2 ± 6.1 cm, 81.7 ± 11.3 kg, 22.8 ± 7.3 % fat; n = 30) and female (23.4 ± 3.1 y, 165.6 ± 8.7 cm, 62.1 ± 9.9 kg, 28.3 ± 7.4 % fat; n = 30) participants were matched according to height and weight to consume 336 ml of the TD or a non-caloric, non-caffeinated placebo (PLA). After a 12 h fast, participants reported for pre-consumption measures of height, weight, heart rate, blood pressure, resting energy expenditure (REE), respiratory exchange ratio (RER), glycerol and free-fatty acid (FFA) concentrations. REE and RER were determined at 60, 120, and 180 min post-consumption. Serum glycerol and FFA concentrations were determined at 30, 60, 120 and 180 min post-consumption.ResultsWhen compared to PLA, TD significantly increased REE at 60, 120 and 180 min (p < 0.05). FFA concentrations were significantly greater in TD compared to PLA at 30, 60, 120 and 180 min post-consumption (p < 0.05). No between-group differences were found in RER.ConclusionAcute TD ingestion significantly increased REE, FFA and glycerol appearance. If sustained, these changes may help to promote weight loss and improve body composition; however, these findings are currently unknown as are the general safety and efficacy of prolonged consumption.
Highlights
To determine the acute effects of ingesting a thermogenic drink (Celsius, Delray Beach, FL) (TD) on changes in metabolism and lipolysis
The purpose of this study examined the acute effects of ingesting a commercially available thermogenic drink (TD) on energy expenditure and lipolysis independent of diet and/or exercise modifications
Caffeine may enhance lipolysis by inhibiting nucleotide phosphodiesterase resulting in increased tissue concentrations of cyclic AMP (cAMP) and activation of hormone-sensitive lipase, which provides further explanation for the increased circulating levels of free fatty acids seen in the present study [12]
Summary
To determine the acute effects of ingesting a thermogenic drink (Celsius, Delray Beach, FL) (TD) on changes in metabolism and lipolysis. The prevalence of individuals who are classified as overweight and obese is a primary health concern due to their relationship to various cardiovascular diseases [1,2] and associated comorbidities [1]. Recent epidemiological data suggests that 31% of the United States (U.S.) population is classified as obese, according to body mass index (BMI). Standards, while 65% is classified as overweight [3]. In addition to reducing medical costs, weight loss can reduce risk for cardiovascular disease, improve quality of life and (page number not for citation purposes). As a result the use of nutritional supplements to aid weight loss has increased in popularity, with consumers spending an estimated $37.1 billion per year [7]
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