Abstract
Several studies have linked increased intake of dietary fibre to improvement in the management of body weight. Dietary fibre from resistant starch (RS) has been shown to have an impact on food intake in normal weight individuals, but its role in obesity is unknown. The present study aimed to investigate the short-term effects of RS on appetite, satiety and postprandial metabolism in overweight/obese subjects. In this single-blind randomized crossover study, overweight/obese healthy males consumed a test breakfast and lunch containing either 48 g RS or a placebo. Postprandial qualitative appetite, glucose, insulin, and GLP-1 were measured every 30 min for 7 h. Energy intake values from an ad libitum dinner and for a 24-h period were assessed. Acute consumption of RS at breakfast/lunch significantly reduced the energy intake at the ad libitum dinner (p = 0.017). No significant effect over 24 h or qualitative feelings of satiety were observed. Significant treatment × time effects were found for postprandial glucose (p = 0.004) for RS compared to placebo, with a trend for higher C-peptide concentrations following RS. The postprandial insulin and GLP-1 responses were not significantly different. RS may indeed have short-term beneficial effects in obese individuals.
Highlights
The prevalence of obesity and being overweight has been widely reported over the past 20 years [1,2,3,4,5]
The consumption of 48 g of resistant starch (RS) divided between breakfast and lunch resulted in a reduction in the energy intake at the ad libitum test meal consumed at dinner compared with that of the placebo
We demonstrated that RS acutely and significantly (p = 0.017) reduces food intake at an ad libitum meal in overweight/obese men compared with placebo
Summary
The prevalence of obesity and being overweight has been widely reported over the past 20 years [1,2,3,4,5]. Obesity is a problem in high-income countries and low- and middle-income countries, where the prevalence of the condition has increased dramatically, especially in urban areas [7]. Obesity is a complex chronic condition, lifestyle modifications that include modifying food behavior may be crucial in obesity management [8]. Several studies have shown an association of increased intake of dietary fibre with improvement in the management of body weight [9,10,11,12,13]. The effect of dietary fibre on weight regulation is manifested through different mechanisms, including stabilising interprandial blood glucose, food intake reductions, delayed gastric emptying time, and intestinal hormone response alterations after fibre consumption [13,14,15]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
