Acute coronary syndrome in a Crohn's disease patient treated with adalimumab

Abstract

Dear Sir, Anti-TNF therapy is increasingly used to treat inflammatory bowel disease (IBD). While some reports indicate that anti-TNF therapy may increase the risk of arterial thrombosis in patients with rheumatoid arthritis (RA),1,2 only one case of acute coronary syndrome (ACS) has been reported in a patient treated with anti-TNF therapy for Crohn's disease (CD).3 We report here a case of acute coronary syndrome that occurred a few days after adalimumab therapy initiation in a CD patient. A 48-year-old man, diagnosed with ileal CD in 1997, was started with HUMIRA® (adalimumab) in January …