Acute Corneal Hydrops in Down Syndrome

Shinji Makino

doi:10.4172/2165-7920.1000235

Abstract

We report a case of severe acute corneal hydrops in a 32-year-old woman with keratoconus associated with Down syndrome. The anterior segment of her right eye showed an extremely diffuse edematous ectasia of acute corneal hydrops. She was observed rubbing her right eye because of itchiness and discomfort in the eye. Complete resolution of the corneal edema and a central corneal scar was seen at the 6th week of follow-up.

Highlights

Keratoconus is a condition in which the cornea assumes a conical shape as a result of noninflammatory thinning of the corneal stroma
Acute keratoconus or corneal hydrops is a frequent feature in these patients leading to a further decrease in visual acuity and a mostly central corneal opacification [2]
A 32-year-old woman with Down syndrome and keratoconus was referred to our hospital with a one week history of ocular pain due to corneal hydrops in her right eye

Summary

Introduction

Keratoconus is a condition in which the cornea assumes a conical shape as a result of noninflammatory thinning of the corneal stroma. An incidence of up to 15% in patients with Down syndrome has been reported in the literature [1]. Acute keratoconus or corneal hydrops is a frequent feature in these patients leading to a further decrease in visual acuity and a mostly central corneal opacification [2]. We report a case of severe acute corneal hydrops in Down syndrome.

Results

Conclusion