Abstract

Acute Colonic pseudo-obstruction (Ogilvie’s syndrome) is common occurrence in both the ICU and longterm acute care units. If not treated in time, it may lead to Colonic perforation or ischemia. Recent report showed that intravenous neostigmine, an acetylcholienastrase inhibitor, produces rapid colonic decompression in patients with acute colonic pseudo-obstruction (ACPO). We report four cases of acute colonic pseudo-obstruction in critical care unit and the response of neostigmine therapy.

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