Abstract
Previous data has shown that exercise can result in the release of myocellular constituents. This study assessed the acute changes in plasma amines and markers of purine degradation following exercise. Following an overnight fast subjects (n = 6, 26±6y; 82.7±21.6kg; 57.1±9.3ml.kg−1.min−1) undertook running or cycling, in a randomised order with trials separated by 1 week. Exercise consisted of a 60 min run at 70% peak speed, or 5 repeated Wingate’s (30s cycle sprint, 2min active recovery). Blood samples were drawn pre, and at 0, 5, 30, 360min and 24hrs following exercise. Carnosine was 30% higher following Wingate sprints than running, while taurine was higher following running with the opposite release profile evident following repeated Wingate’s. Markers of purine degradation (uric acid, ammonia) and creatine where significantly elevated following both exercise bouts, but to a higher degree following Wingate’s. Creatine kinase immediately post running exercise was increased. CONCLUSION: Prolonged or intense exercise results in the release of Carnosine and Taurine, which due to their preferential distributions in type I and II muscle fibres may provide unique markers of fibre specific muscle damage.
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