Abstract
Acute bony and joint infections are serious musculoskeletal affections that are mainly encountered during childhood. A multi-disciplinary approach is required for prompt diagnosis and treatment to decrease long-term morbidity and loss of function. Involvement of multiple specialties including paediatricians, orthopaedic surgeons, infectious disease, emergency medicine, intensive care, laboratory and radiology specialists is necessary. Diagnosis requires high level of suspicion particularly in neonates and very young children. Knowledge of the relevant bacterial pathogens, their age prevalence and antibiotic sensitivity profile are essential for successful medical treatment. Antibiotic resistance and the emergence of virulent bacterial strains like CA-MRSA and PVL S. aureus are other challenging aspects of musculo-skeletal infections. Adequate antibiotic therapy duration is very controversial aspect in bony and joint infection and should be individualized according to the virulence of the infecting organism; the clinical improvement and laboratory follow up. Finally, surgical treatment might be needed in particular for acute joint infections and should be done timely without delay when indicated.
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