Abstract
Acute atrial wall stretch and the efficacy of flecainide-induced conversion of atrial fibrillation
Highlights
The success rate of drug-administered cardioversion of atrial fibrillation (AF) depends on many factors such as gender, duration of AF, presence of structural heart disease and so forth
Symptomatic < 24 hours AF was shown to be a valid predictor for spontaneous cardioversion, followed by a normal left ventricular function while the size of the left atrium (LA) was of no value [6]
With the purpose to determine the contribution of NTproBNP to the selection of patients suitable for a successful cardioversion of AF with flecainide, Amin and coworkers carried out a prospective study under very specific clinical circumstances: symptomatic < 24 hours AF, neither structural heart disease, nor left ventricular ejection fraction < 55 %, nor severe comorbidity [3]
Summary
The success rate of drug-administered cardioversion of AF depends on many factors such as gender, duration of AF, presence of structural heart disease and so forth. The conversion success rate of flecainide is 67–92 % at 6 hours provided AF is of < 24 hours onset and its safety is very acceptable.
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