Acute and Sub-Acute Toxicity Studies of Dhatupaushtik Churna

doi:10.26538/tjnpr/v5i10.11

Abstract

a peer-reviewed, open access online international journal which publishes original research papers. The journal welcomes submission from scholars and experts for possible publication from all over the world. The scope of the journal includes: Pharmaceutical research, chemistry and biochemistry of naturally occurring compounds, biological evaluation of crude extracts, ethnomedicine, traditional and complementary medicine, ethnopharmacology, biomedical research, Biotechnology, Evaluation of natural substances of land and sea and of plants, microbes and animals, pharmacognosy, bioavailability, clinical, pharmacological, toxicological studies and pharmacokinetics of phytochemicals, Isolation and characterization of compounds, structure elucidation, synthesis and experimental biosynthesis of natural Product as well as developments of methods in these areas are welcomed in the journal.

Highlights

For the development of novel medications, a toxicological examination is deemed critical
Experimental animals Adult healthy male Swiss mice weighing 20-25 g and male Wistar rats weighing between 150-200 g were used to evaluate acute and subacute toxicity studies
Subacute toxicity study The subacute toxicity of Dhatupaushtik churna aqueous extract was performed following the method of Halim et al.[14] and Mondal et al.[11]

Summary

Introduction

For the development of novel medications, a toxicological examination is deemed critical. Folkloric usage of herbs for treating diseases without attention to their harmful effects may lead to future health issues.[1] The use of plants or plant components is fast growing because they have fewer or no side effects than synthetic medications.[2] According to World Health Organization (WHO) data, more than 80% of the world's population, primarily from developing countries, rely on herbal medicines for their healthcare needs. For the simple fact that it is effective and has fewer side effects, an increasing number of people are turning to Ayurveda to live a disease-free life Ayurvedic remedies such as Dhatupaushtik churna have a long history of use, till researchers are extolling their effectiveness.

Materials and Methods

Results and Discussion

Conclusion