Abstract
Preliminary evaluation of hepatoprotective and nephroprotective effects of Prosopis ruscifolia Griseb. leaves extract in miceMaría S. Soverina, Miguel A. Campuzano-Bublitz, Juan R. Centurión, Antonia K. Galeano, María L. Kennedy
Highlights
Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the secreted insulin cannot effectively used by the body
The animals were assigned to different groups and treated with a single dose of solvent, Pr (100 mg/Kg, p.o.), tolbutamide (100 mg/Kg, p.o.) or insulin (5 IU/kg, i.p.); Pr extract was administered to normoglycemic rats (100 mg/kg, p.o.)
The results show that Pr extract significantly reduces blood glucose level in hyperglycemic rats (p < 0.01) 24 h after administration of a single oral dose of 100 mg/Kg
Summary
Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin (type I diabetes) or when the secreted insulin cannot effectively used by the body (type II diabetes). According to a survey conducted in 2011, 9.7% of the population was diagnosed with some form of diabetes, the prevalence in women being 11% and in men 7.9% (Cañete, 2011). This represents an increase, considering that in the survey conducted in 1992 it had been estimated that the prevalence of diabetes in Paraguay was 6.5% (Jiménez et al, 1998). These data demonstrate that diabetes is a disease that has major impact on the Paraguayan population, so the management of the disease demands
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
