Abstract
IntroductionEpstein Barr virus (EBV) is a human herpes virus 4, transmitted through intimate contact between susceptible persons and asymptomatic EBV shedders. It usually presents with fever, pharyngitis and lymphadenopathy. Majority of individuals with primary EBV infection recover uneventfully. Acute Acalculous Cholecystitis (AAC) is usually seen in hospitalized and critically ill patients with major trauma, shock, severe sepsis, total parenteral nutrition and mechanical ventilation.Case presentationWe report a 25-year- old woman presented with acute Epstein-Barr Virus (EBV)infection and hepatobiliary iminodiacetic acid (HIDA) scan confirmed presence of Acute Acalculous Cholecystitis (AAC). Conservative management was advised initially, but she had a laparoscopic cholecystectomy due to intolerable abdominal pain.ConclusionAAC is a rare complication of acute EBV infection and it is usually managed conservatively, although our patient had laparoscopic cholecystectomy due to intolerable abdominal pain.
Highlights
Epstein Barr virus (EBV) is a human herpes virus 4, transmitted through intimate contact between susceptible persons and asymptomatic Epstein-Barr Virus (EBV) shedders
We report a 25-year- old woman who presented with fever T 38.6C, sore throat, abdominal pain, nausea, vomiting and anorexia
Kottanattu et al reported in a systemic review of the literature, 37 cases of Acalculous Cholecystitis (AAC) in primary acute EBV infection which were published between 1966 and 2016, all cases always recovered without surgery or corticosteroids, following a hospital stay of 25 days or less [8]
Summary
Epstein-Barr Virus (EBV) is a human herpes virus 4, transmitted through intimate contact between susceptible persons and asymptomatic EBV shedders. It usually presents with fever, pharyngitis and lymphadenopathy [1]. Majority of individuals with primary EBV infection recover uneventfully [2]. Acute Acalculous Cholecystitis (AAC) is usually seen in hospitalized and critically ill patients with major trauma, shock, severe sepsis, total parenteral nutrition and mechanical ventilation [3,4]. This work has been reported in line with the surgical case report (SCARE) criteria [5]
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