Abstract
To the Editor: I read with interest the ESBY study (Electrical Stimulation versus coronary artery BYpass surgery in severe angina pectoris) by Mannheimer et al.1 They found that spinal cord stimulation (SCS) has antianginal and anti-ischemic effects in severe angina pectoris and concluded that CABG and SCS are equivalent methods in terms of symptom relief. In a previous report,2 these authors showed that myocardial extraction of β-endorphin during control atrial pacing changed to release at the maximum pacing rate during SCS. Furthermore, their results indicate local myocardial turnover of β-endorphin, leuenkephalin, and calcitonin-gene–related …
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