Abstract
Background:The systematic review protocol is aim to evaluate the efficacy and safety of acupuncture in the treatment of atopic dermatitis (AD).Methods:We will search the database on the Cochrane Library, PubMed, Medline, Excerpta Medica Database, Chinese Biomedical Literature Database, PsychINFO, China National Knowledge Infrastructure, Wanfang data, Chinese Scientific Journal Database, including studies and published systematic review in the reference list and grey. And will use Cochrane Collaboration's tools to evaluate the risk of bias of the included randomized controlled trials. The Review Manager 5.3 will be used to synthesize collected data.Results:This study will assess the safety and effectiveness based on current evidence of acupuncture for AD, especially scoring atopic dermatitis, eczema area, and severity index, patient-oriented eczema measure, and quality of life.Conclusion:This study will provide high-quality recently evidence for evaluating the efficacy of acupuncture for patients with AD.PROSPERO registration number: CRD42019135919.
Highlights
Atopic dermatitis (AD) is a complex chronic inflammatory disease of the skin, which is closely related to other atopic and allergic diseases, including asthma and atopic rhinitis.[1,2,3]
It is necessary to make a meta-analysis of atopic dermatitis (AD) to evaluate the effectiveness and safety of acupuncture in the treatment process
The protocol was registered on Prospero (CRD42019135919)
Summary
The protocol was registered on Prospero (CRD42019135919). The content followed preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P).[16]. This review will include all randomized controlled trials (RCTs) in English or Chinese and without the restriction of publication type. Non-RCTs, quasi-RCTs, uncontrolled trials, case series, case reports, crossover studies, letters, and laboratory studies will be excluded. Patients with AD were diagnosed according to Hanifin and Rajka criteria or the UK refinement were included.[17,18,19] Information relating to their age, sex, race, education, nationality, or economic status is not taken into account
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