Actualización en materia de cirugía ortopédica y traumatología de la repercusión clínica de la utilización de PRGF: plasm rich in growth factors

Abstract

Objective: Update on plasma rich in growth factors (PRGF) in the field of orthopedic surgery and traumatology. Method: Review of 136 studies on PRGF relevant in the field of orthopedic surgery and traumatology published in the last 10 years. Results: The largest number of studies on PRGF has been performed in the field of osteoarthritis of the knee (25%), followed closely by the comparative studies between PRGF and hyaluronic acid (19%). The studies on ligamentous and tendinous pathology (14%), the joint pathology different from the knee (10%).The remaining studies addressed pseudoarthrosis, osteonecrosis and nerve regeneration among others. The most commonly used platelet products were Plasma Rich in Platelets (73%), Plasma Rich in Growth Factors (15%) and Plasma Rich in Fibrin (12%). Conclusions: To document the preparation of platelet prod-ucts, establish the precise concentration of growth factors and carry out long-term follow-up is es-sential for future studies.