Abstract
IntroductionHemolytic anemias (HA) are a complex group of disorders resulting in premature destruction of red blood cells or hemolysis. Common laboratory data are: anemia with increased reticulocyte, elevated values for indirect bilirubin and lactate dehydrogenase (LDH), as well as decreased level of haptoglobin and hemopexin. ClasificationHemolytic anemias are grouped in two big categories: hereditary HA, due to a half-life reduction of red cells as consequence to congenital structural defects (membranopathies, erythro-enzymopathies, thalassemia and hemoglobinopathies); and acquired HA which are divided in immune and non-immune mediated, highlighting its frequency the autoimmune anemias and its severity the thrombotic microangiopathies. Its distinctive features require different management strategies.
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