Abstract
One of the serious negative consequences of the HIV infection epidemic is the involvement of women of reproductive age and children into the epidemic process. The problem of vertical HIV infection transmission does not lose its relevance and causes the need for continuous monitoring of measures to prevent the transmission of HIV from mother to child. The aim of the study is to evaluate the effectiveness of a set of measures to prevent the transmission of HIV infection from mother to child in the South of Russia.Materials and methods. The common methods of variation statistics were used in the work to analyze the data from the reporting forms of monitoring by Rospotrebnadzor «Imformation on measures for the prevention of HIV infection, hepatitis B and C, detection and treatment of HIV patients» and federal reporting forms N 61 «Information on contingents of patients with a disease caused by a human immunodeficiency virus (HIV)» for 2016 and 2017, presented by the territorial Centers for Prevention and Control of AIDS of 15 RF subjects of the Southern Federal District and the North Caucasus Federal District.Results. In 2017, compared to 2016, the decrease in the number of births in HIV-positive women was traced on the territory of the South of Russia. In 2017, target levels of mother-child coverage with chemoprevention of mother-to-child transmission of HIV during pregnancy (over 92%) and during childbirth (more than 93,5%) were achieved in the Southern Federal District and the North Caucasus Federal District. A high proportion of women with a detectable level of HIV replication before birth was revealed.Conclusion. The implementation of the recommended by standards preventive measures and the provision of antiretroviral drugs allowed to significantly increase the coverage of HIV infected pregnant women and their newborns with antiretroviral prophylactic treatment by 2018 which prevented HIV infection transmission from mothers to 8840 children. The problems that prevent the implementation of the full range of measures for the prevention of the vertical transmission of HIV in the South of Russia are identified and approaches for their solution are suggested.
Highlights
One of the serious negative consequences of the human immunodeficiency virus (HIV) infection epidemic is the involvement of women of reproductive age and children into the epidemic process
The mean prevalence of the Beijing and Latin-American Mediterranean (LAM) genotypes in the above studied areas was 56.1% and 11.8%, respectively
These results demonstrate a significant prevalence of the epidemiologically important Beijing genotype, exceeding that in its endemic Asian region
Summary
One of the serious negative consequences of the HIV infection epidemic is the involvement of women of reproductive age and children into the epidemic process. Цель исследования – оценка эффективности комплекса мероприятий по профилактике передачи ВИЧ-инфекции от матери к ребенку на Юге России. Динамика охвата ВИЧ-инфицированных женщин и рожденных ими детей антиретровирусной профилактикой в ЮФО и СКФО за период с 2006 по 2017 г. На Юге России достигнуты целевые уровни охвата пар мать – дитя химиопрофилактикой передачи ВИЧ-инфекции от матери к ребенку во время беременности (более 92%) и во время родов (более 93,5%).
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