Activity of Some Disinfectants, Detergents and Essential Oils on Growth of the yeast Candida albicans

Abstract

The study was conducted for estimating antifungal activity against Candida albicans of ten essential oil, garlic and onion juice, eight disinfectants and detergents by using agar diffusion well method. The results showed high activity of clove oil, onion juice 50%, thyme oil, hydrogen peroxide (H2O2), lugol's iodine and detol for all the five concentration, sodium chloride (NaCl) and sodium carbonate (Na2CO3) at 5%, while the effect of apple cider vinegar were at 60% and 80%. Sodium hypochlorite showed moderate activity at all concentration. The result of combination between clove oil and coconut oil led to synergistic effect while the combination between each of (1, 2, 3 % H2O2 with each of apple cider vinegar and NaCl), (sodium chloride with apple cider vinegar) and (pumpkin oil with clove oil) lead to antagonism as well as the same results were reported when apple cider vinegar mixed with each of (thyme oil) and (clove oil with coconut oil). On the other hand, there is no synergistic or antagonistic effect of combination between 4-5% of H2O2 with apple cider vinegar and NaCl solution to the growth of C. albicans. It was concluded that solitary use of compounds (clove oil, onion juice, thyme oil, H2O2, NaCl, lugol's iodine, detol, and apple cider vinegar) was associated with high antifungal response regarding C. albicans; efficacy was reduced when used in combination. In exception to above finding synergistic effect was identified when a combination between clove oil and coconut oil.