Activity of Edible Mushrooms Against the Growth of Human T4 Leukemic Cancer Cells, HeLa Cervical Cancer Cells, and Plasmodium falciparum

Abstract

ABSTRACT Several edible Hymenomycete mushroom species have been screened as possible inhibitors of human T4 leukemic cancer cells, HeLa cervical cancer cells, Plasmodium falciparum (a pyrimethamine resistant malarial parasite), and six pathogenic microorganisms. Grifola frondosa, Ganoderma lucidum, Lentinula edodes, and Laetiporus sulphureus demonstrated activity against human T4 leukemic cancer cells. Grifola frondosa, Ganoderma lucidum, Lentinula edodes, and Lentinula aurantiacum demonstrated activity against HeLa cervical cancer cells. Pofyporus umbellatus, Russula xerampelina, Ganoderma lucidum, Trametes versicolor, Lentinula aurantiacum, Laetiporus sulphureus, Boletus variipes. Boletus queletii, Grifola frondosa, and Lentinula edodes demonstrated activity against Plasmodium falciparum. No activity was observed against the pathogenic microorganisms.