Abstract
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Numerous studies have demonstrated that ionophores alter rumen metabolism
(1984) showed that 36-40% of radiolabelled monensin was absorbed from the gastrointestinal tract of calves and Armstrong and Spears (1988) supplied data on changes of intermediary metabolism of heifers following intravenous ionophore administration
In this paper we examined the effect of long-term monensin feeding on activity of nine intracellular enzymes in rumen mucosa and liver of steers
Summary
Numerous studies have demonstrated that ionophores alter rumen metabolism (review Bergen and Bates 1984). Typical ionophore-induced effects include the increase of propionate production in the rumen and the decrease of production of acetate, butyrate and methane. Similar changes in fermentation stoichiometry were observed in ruminant hindgut (Marounek et al 1990). Recent research provided evidence for an effect of ionophores on metabolism in ruminants independent of alterations in rumen and hindgut microbial metabolism. Experiments of Davison (1984) showed that 36-40% of radiolabelled monensin was absorbed from the gastrointestinal tract of calves and Armstrong and Spears (1988) supplied data on changes of intermediary metabolism of heifers following intravenous ionophore administration. In this paper we examined the effect of long-term monensin feeding on activity of nine intracellular enzymes in rumen mucosa and liver of steers
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