Abstract

Cyclic lipodepsipeptides (CLDP) are produced by bacteria and have been studied extensively for their antimicrobial activities and wetting properties. Bacteria derived from opportunistically sampled mammals, including opossum, skunk, raccoon, boar, and deer, in Oklahoma were cultured and shown to produce CLDPs including viscosin, serratiamycin, and surfactin. Two dimensional NMR studies and MS analysis lead to 3 new serrawettin W2 analogues. Their activities against several biological targets were assessed.

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