Abstract
2- and 2,5-substituted thiazolidine derivatives have been evaluated as potential anti-radiation agents in mice. Comparison with anti-radiation agent controls, shows the interest of this series: good activity at low doses ( LD 50 1 8 ), low toxicity and duration of the radioprotective effects varied according to the compound. Some thiazolidines are more active at low doses than the equimolecular quantity of cysteamine they release in vivo.
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