Abstract

Active surveillance of the spread of mcr-1-positive E coli

Highlights

  • Active surveillance of the spread of mcr-1-positive E coli In The Lancet Microbe, Yan Jiang and colleagues[1] present the results of a retrospective study of the prevalence and emergence of mcr-1 positive Escherichia coli in hospitalised patients in China in the decade between 2008 and 2017

  • The newly published study elaborates on the potential risk factors and outcomes of infection in patients infected with mcr-1-positive and mcr-1-negative E coli, such as health-care contact and antibiotic usage history, which was consistent with previous studies.[2] mcr-1, the first mobile colistin resistance gene mediated by plasmids, was discovered almost 5 years ago.[4]

  • Mcr-1 is speculated to have originated in livestock, because colistin has been widely used in agriculture as a growth promoter since the 1970s

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Summary

Introduction

In The Lancet Microbe, Yan Jiang and colleagues[1] present the results of a retrospective study of the prevalence and emergence of mcr-1 positive Escherichia coli in hospitalised patients in China in the decade between 2008 and 2017.

Results
Conclusion

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