Abstract
Active surveillance of the spread of mcr-1-positive E coli
Highlights
Active surveillance of the spread of mcr-1-positive E coli In The Lancet Microbe, Yan Jiang and colleagues[1] present the results of a retrospective study of the prevalence and emergence of mcr-1 positive Escherichia coli in hospitalised patients in China in the decade between 2008 and 2017
The newly published study elaborates on the potential risk factors and outcomes of infection in patients infected with mcr-1-positive and mcr-1-negative E coli, such as health-care contact and antibiotic usage history, which was consistent with previous studies.[2] mcr-1, the first mobile colistin resistance gene mediated by plasmids, was discovered almost 5 years ago.[4]
Mcr-1 is speculated to have originated in livestock, because colistin has been widely used in agriculture as a growth promoter since the 1970s
Summary
In The Lancet Microbe, Yan Jiang and colleagues[1] present the results of a retrospective study of the prevalence and emergence of mcr-1 positive Escherichia coli in hospitalised patients in China in the decade between 2008 and 2017.
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