Abstract

Two diesters of the new diterpene alcohol 20-deoxy-5ζ-hydroxyphorbol, milliamines H and I, have been isolated from EUPHORBIA MILII. Both carry an acelate group in position 13. In position 12, milliamine H contains a 2-[2-(methylamino)benzoyl]aminobenzoyl dipeplide moiely and milliamine I a 2-(2-hydroxybenzoyl)aminobenzoyl moiety. They exhibil weak (H) or virtually no (I) irritant activities.

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