Abstract
Background: The use of herbs as traditional medicine in Indonesia is increasing, with more than 40% of Indonesia's population utilizing them. White oyster mushroom (Pleurotus Ostreatus) is a fungus that has various therapeutic effects including antioxidant, anti-inflammatory, anti-bacterial, anti-cholesterol, and anti-cancer properties. This mushroom contains many active substances in its secondary metabolites which have pharmacological effects. The purpose of this study was to identify the active compounds in the ethanolic extract of white oyster mushroom that will form the extract profile and become the basis for drug development. Methods: The active compound test used High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography with Mass Spectrometer (LC-MS). Ethanolic extract of white oyster mushroom was processed by 70% alcohol maceration, evaporation, and thickening. Results: The results of the HPLC test showed that the ethanolic extract of white oyster mushroom contained cinnamic acid and rutin, while the LC-MS test showed the presence of p-coumaric acid, Ascorbic acid, Linoleic acid, 9-Eicosene (E), Niacinamide, Veritric acid, Syringic acid, Ergosterol. Conclusions: The active compounds that were detected in the ethanolic extract of white oyster mushroom showed that the extract had the potential for antioxidant and anti-inflammatory activity.
Highlights
White oyster mushroom (Pleurotus ostreatus) is a very popular food source, belonging to the Basidiomycetes class of fungi.[1,2] This mushroom has a very high nutritional value and various secondary metabolites that have potential for pharmacological effects.[1,3] Two of the most important pharmacological effects of mushrooms are the antioxidant and anti-inflammatory effects
We studied the marker compounds and analyzed the profile of ethanolic extract of white oyster mushroom, to strengthen scientific data regarding the effects of white oyster mushrooms and facilitate their development into standardized herbs
The ethanolic extract of white oyster mushroom was made from 5 kg of wet simplicia of oyster mushrooms, of which only the umbrella part was taken, so that it was reduced to 3 kg
Summary
White oyster mushroom (Pleurotus ostreatus) is a very popular food source, belonging to the Basidiomycetes class of fungi.[1,2] This mushroom has a very high nutritional value and various secondary metabolites that have potential for pharmacological effects.[1,3] Two of the most important pharmacological effects of mushrooms are the antioxidant and anti-inflammatory effects. White oyster mushrooms, which are believed to have antioxidant effects, include vitamin C, beta-carotene, selenium, ergothioneine, and phenolic components. Phenolic components are the main components that affect its antioxidant activity.[6,7,8] Previous studies have shown the antioxidant effect of ethanolic extract of white oyster mushroom which can prevent the increase in MDA and decrease in lung surface density (S/V).[5]. White oyster mushroom (Pleurotus Ostreatus) is a fungus that has various therapeutic effects including antioxidant, antiinflammatory, anti-bacterial, anti-cholesterol, and anti-cancer properties. This mushroom contains many active substances in its secondary metabolites which have pharmacological effects. Conclusions: The active compounds that were detected in the ethanolic extract of white oyster mushroom showed that the extract had the potential for antioxidant and anti-inflammatory activity
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
