Abstract
Patients with uremia often develop bleeding diatheses at cutaneous or incisional sites, intra-abdominal or intracranial hemorrhages. We report active bleeding in a uremic patient after she received a temporary catheter for hemodialysis therapy. Active bleeding was considered to be due to platelet dysfunction, diagnosed by prolonged skin bleeding time. Her spontaneous bleeding gradually vanished after receiving blood transfusions with cryoprecipitate. The assessment of skin bleeding time in uremic patients with active bleeding is a crucial step to identify platelet dysfunction.
Highlights
Uremia is a serious subsequent complication of renal function deterioration, mostly caused by hypertension and diabetes [1]
Uremia can cause uremic bleeding, which leads to serious complications, including coma, seizures, cardiac arrest, and even death
After a series of examinations, a prolonged skin bleeding time was detected; the diagnosis was platelet dysfunction. Her spontaneous bleeding gradually vanished after receiving blood transfusions with cryoprecipitate
Summary
Uremia is a serious subsequent complication of renal function deterioration, mostly caused by hypertension and diabetes [1]. Uremia causes a medical syndrome associated with fluid overloading, electrolyte and hormone imbalances, and metabolic aberrations. Hyperkalemia, metabolic acidosis, and generalized edema, especially pulmonary edema, cause cardiovascular diseases to worsen, which can lead to death. The macromolecule uremic toxins, such as parathyroid hormone, β2-microglobulin, polyamines, and advanced glycation end products, are considered to result in long-term organ damage in uremic patients [2]. Uremia can cause uremic bleeding, which leads to serious complications, including coma, seizures, cardiac arrest, and even death. Severe uremia can cause clinically spontaneous bleeding, such as gastrointestinal hemorrhage, intracranial bleeding, and internal bleeding. © Copyright iMedPub | This article is available from: http://medical-case-reports.imedpub.com/
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