Abstract

Jailed populations exhibit high rates of tuberculosis (TB) infection and active disease. A cross-sectional study was performed to estimate the prevalence of latent and active TB and to identify factors associated with latent infection in inmates. The prevalence of latent TB was 49%, and the prevalence of active TB was 0.4%. The presence of a Bacille Calmette-Guérin (BCG) scar (prevalence ratio (PR)=1.65; 95% confidence interval (CI): 1.09-2.50; p=0.0162) and the World Health Organization (WHO) score for active TB in prisons (PR=1.07; 95% CI: 1.01-1.14; p=0.0181) were correlated with infection. The identification of associated factors and the prevalence of latent and active TB allows the development of plans to control this disease in jails.

Highlights

  • Jailed populations exhibit high rates of tuberculosis (TB) infection and active disease

  • The presence of a Bacille Calmette-Guérin (BCG) scar (prevalence ratio (PR)=1.65; 95% confidence interval (CI): 1.09-2.50; p=0.0162) and any increase in the World Health Organization (WHO) clinical score (PR=1.07; 95% CI: 1.01-1.14; p=0.0181) were statistically significant in the multivariate model

  • In our study, the clinical scores were correlated with Latent tuberculosis infection (LTBI), suggesting that the WHO symptoms are associated with latent infection

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Summary

Introduction

Jailed populations exhibit high rates of tuberculosis (TB) infection and active disease. Latent tuberculosis infection (LTBI) predisposes inmates to a greater risk of progression to active disease and increases the transmission rates inside and outside of the jail system[4]. The aim of this study was to estimate the prevalence of latent and active TB infection and to describe the risk factors associated with latent TB among inmates in a jail in the central-western region of Brazil.

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