Abstract
ALTERATION of cellular senescence following transplantation may be associated with posttransplant carcinogenesis. A study of the aging of donor grafts also may be important for the donor selection in living-related or cadeveric orthotopic liver transplantation (OLT). Telomere and telomerase are involved in the central timing mechanisms for cellular aging. Here, we studied telomerase activity in livers from various rat OLT models.
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