Abstract
Hydrogen peroxide is a natural oxidant formed and used in biological systems, since Evolution provided molecular oxygen on earth. Mitochondria and peroxisomes are the essential sites of the molecular oxygen uptake by cells. Proteins such as D-aminoacid oxidase, urate oxidase, galactose oxidase, amine oxidases are able to produce hydrogen peroxide in O2-mediated oxidation of the corresponding substrate [1]. In order to control the hydrogen peroxide level in these sub-cellular compartments, catalase is present and catalyzes the H2O2 dismutation in water and dioxygen at a rate of 105 cycles/second [2].
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