Abstract
The ability of carba-analogs of oxytocin to activate adenylate cyclase was followed on the crude enzyme preparation from rat renal medulla. Their stimulating effects on adenylate cyclase activity were in a correlation with their antidiuretic potency. There is discussed the dependence of the affinity of carba-analogs of oxytocin to stimulate adenylate cyclase and their antidiuretic potency on the character of changes in the primary structure of these drugs.
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More From: Collection of Czechoslovak Chemical Communications
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