Abstract
Activation of a bacterial killing machine.
Highlights
Microbes in Health and Disease Theme, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom a1111111111 a1111111111 a1111111111 a1111111111 a1111111111
Previous work investigating phage therapy as an alternative treatment for drug-resistant E. faecalis noted that phage-infected cells induce expression of the T7SS locus [21]
In a ΔireK strain, the T7SS genes were no longer induced upon phage predation, and phage-induced antibacterial antagonism was abolished [19]. These results demonstrate that E. faecalis has a potent antibacterial T7SS that is transcriptionally activated through a membrane-bound kinase by environmental conditions that trigger membrane damage
Summary
Microbes in Health and Disease Theme, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom a1111111111 a1111111111 a1111111111 a1111111111 a1111111111. Microbes in Health and Disease Theme, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom In gram-negative bacteria, type V and type VI secretion systems (T5SS and T6SS) mediate interbacterial antagonism via toxin delivery to neighbouring cells.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
