Abstract
APC-PCI was measured in acid citrate plasma by means of a newly developed sandwich ELISA ( median normal value 0.13 ng/mL, range 0.07-0.26, n = 16). The low pH of the plasma prevents ex vivo for- mation of further APC-PCI. Levels of APC-PCI and protein C were monitored (daily to alternate days) in 135 consecutive critically ill patients, 53 of whom had sepsis during the obser- vation period. Four patients were ex- cluded because of incomplete data. The state of p rotein C activation to APC was categorized as non-activated, moderately activated or highly activated, based on maximum APC-PCI values in relation to the normal range.
Highlights
There is considerable uncertainty about the reproducibility of the various instruments used to measure dyspnea, their ability to reflect changes in symptoms, whether they accurately reflect the patient’s experience and if its evolution is similar between acute heart failure syndrome patients and nonacute heart failure syndrome patients
Results of this study show that early tracheostomy, if perioperative complications
We looked at the use of postwith tracheostomies performed in the critical care unit of a tertiary procedure chest radiography (CXR)
Summary
There is considerable uncertainty about the reproducibility of the various instruments used to measure dyspnea, their ability to reflect changes in symptoms, whether they accurately reflect the patient’s experience and if its evolution is similar between acute heart failure syndrome patients and nonacute heart failure syndrome patients. Conclusions Our data demonstrate that critically ill patients may be exposed to a higher FiO2 than that required to maintain adequate oxygenation These results highlight an area of ICU care that has received little study, with no published clinical trials examining the effect of FiO2 on outcome. Results Age, sex, the underlying disease and tumour stage (TNM classification), type of previous anticancer treatment, performance status, severity scores (APACHE II, Simplified Acute Physiology Score II, Sequential Organ Failure Assessment), ICU and hospital mortalities and hospital outcome at 3, 6 and 12 months were analysed. Clinical data of 277 post-transplantation patients admitted to the ICU were collected at admission and the SAPS 3 and APACHE II score calculated with respective estimated mortality rates.
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