Abstract
Summary An experimental hyperuricosuria was induced in the rat by potassium oxonate and the uricosuric action of 4-prenyl-1,2-diphenyl1-3,5-pyrazolidinedione (DA 2370 * ), phenylbutazone (PBZ) and zoxazolamine was verified. DA 2370 revealed a clear activity, however its action is slightly lower than that of PBZ. Both drugs showed a proportional uricosuric activity; zoxazolamine resulted active only at the highest dose.
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