Abstract

SummaryCobra venom, cardiotoxin, saponin and drugs of the digitalis series bring about the stoppage of the movements of the excised heart. The cardiac arrest caused by cobra venom, unlike that by saponin and digitalis, is irreversible, i.e., cannot be washed out. Unlike living muscle fibres, glycerinated muscle fibres and actomyosin threads show no contraction under the influence of cobra venom or cardiac drugs. These drugs have no effect on myosin and actin either.

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