Actinomyces and the intrauterine contraceptive device: Aspects of the fluorescent antibody stain

Abstract

Using fluorescein-conjugated globulins specific for Actinomyces israelii and Arachnia propionica, we observed large dispersed actinomycete populations in vaginal smears of several asymptomatic women. Mycelial granules, commonly revealed by the Papanicolaou stain, were not seen. These observations are discussed in regard to the threat of infection and sensitivity of the fluorescent stain.