Acrylamide: New Organic Solvent with Chemically Tunable Viscosity for Rapid Gram-Scale Synthesis of Gold Nanoparticles.

Abstract

Noble metal nanoparticles have demonstrated various biomedical, optical, and electronic applications owing to their unique chemical and physical properties. However, their gram-scale synthesis remains a challenge. We have developed a method for the gram-scale synthesis of gold nanoparticles (AuNPs) using acrylamide (AAm) as a solvent. AAm possesses unique properties such as low melting temperature, high solvating power, and high solubility of its polymer (polyacrylamide(pAAm)) in water. The viscosity of the AAm solvent can be chemically tuned by the polymerization of AAm and addition of a low-volatile diluent, which can stabilize highly concentrated as-synthesized AuNPs in gram quantities. The synthesized AuNPs are substantially stable and catalytically active under high ionic strength conditions owing to the pAAm protection on the particle surface. Further, the synthesis mechanism of the AuNPs has been thoroughly investigated. The versatility of the synthesis method is proved by synthesizing other mono-(Ag and Pd) and bimetallic (Au + Pd and Ag + Pd) nanoparticles using the AAm solvent with controlled viscosity. Importantly, the productivity of this synthetic strategy is the highest among the previously reported gram-scale synthesis methods of AuNPs. To the best of our knowledge, our study presents the use of acrylic monomer as a solvent for the gram-scale synthesis of noble metal nanoparticles for the first time. This study significantly extends the list of solvents with chemically tunable viscosity by including other acrylic reagents for nanomaterial synthesis, functionalization, and catalytic, optical, and electrical reactions under highly localized reaction conditions.