Acrodermatitis enteropathica without diarrhea.

Abstract

Acrodermatitis enteropathica was first recognized by Danbolt and Closs⁴in 1942, although cases had been previously described in the literature under a variety of titles. Further examples of the condition have been reported by Danbolt,^2,3Bloom and Sobel,¹Hodgson-Jones,⁷and Hare and Schlesinger.⁶The disease is now accepted as a clinical entity comprising a cutaneous eruption, gastrointestinal symptoms, and disturbances of growth and development (Sulzberger and Baer).¹⁰It has been well summarized by Dillaha et al.,⁵who also reported the beneficial effects of diiodohydroxyquin (Diodoquin) by mouth as suggested by Schlomovitz.⁹Vedder¹¹noted the occurrence of the condition in a number of siblings. All authors agree on the presence of recurrent attacks of diarrhea or mucoid stools and an erythematous papulovesicular or pustular rash usually surrounding the orifices and on the hands and feet. Paronychia may also be a feature. Thinning