Abstract
IntroductionTumoral calcinosis is an uncommon disorder characterized by the development of calcified masses within the peri-articular soft tissues of large joints, but rarely occurs within the hand.Case presentationWe present the case of a 31-year-old pregnant Indian woman with a three-month history of painful swelling within the tip of her right middle finger following a superficial laceration. She was otherwise well and had normal serum calcium and phosphate levels. Plain radiography demonstrated a dense, lobulated cluster of calcified nodules within the soft tissues of the volar pulp space, consistent with a diagnosis of tumoral calcinosis. This diagnosis was confirmed on the basis of the histopathological examination following surgical excision.ConclusionTo the best of our knowledge, we present the only reported case of acral tumoral calcinosis within the finger, and the first description of its occurrence during pregnancy. We review the etiology, pathogenesis and treatment of tumoral calcinosis.
Highlights
Tumoral calcinosis is an uncommon disorder characterized by the development of calcified masses within the peri-articular soft tissues of large joints, but rarely occurs within the hand.Case presentation: We present the case of a 31-year-old pregnant Indian woman with a three-month history of painful swelling within the tip of her right middle finger following a superficial laceration
Pathogenesis and treatment of tumoral calcinosis
The term tumoral calcinosis was coined by Inclan et al in 1943 [3], who described a familial condition characterized by normal serum calcium levels and elevated or normal serum phosphate levels
Summary
Tumoral calcinosis is an uncommon pathological entity characterized by multiple circumscribed, tumor-like, calcified masses in peri-articular connective tissue These lesions mainly comprise calcium hydroxyapatite crystals and amorphous calcium phosphate [1]. The most common locations of tumoral calcinosis are around the hip joint, elbow, shoulder, foot and wrist joints, with a predisposition for extensor surfaces [1] This condition does not commonly involve the hand, and to the best of our knowledge, we present the first reported case of a post-traumatic acral fingertip lesion occurring during pregnancy. Case presentation A 31-year-old, right-hand-dominant woman of Indian origin presented with a three-month history of increasing swelling overlying the volar tip of her right middle finger She recalled sustaining a superficial laceration to the area with a clean kitchen knife, which was treated successfully by application of a clean, dry dressing. Recovered well with no evidence of recurrence at her six-month follow-up examination
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