Acquired Hemophilia A: A Rare Presentation with Buccal Bleeding: A Case Report

Abstract

Introduction: Acquired Hemophilia A (AHA) is a rare but potentially lifethreatening bleeding disorder characterized by autoantibodies for coagulation factor VIII. Awareness of AHA different presentations may save patients’ lives. However, there is diverse presentation of AHA reported in medical literature. Aim: To report AHA case with rare presentation of buccal bleeding and raise awareness of a such condition. Case: We reported a case of AHA in a patient with chronic medical condition that presented with buccal mucosal bleed. Despite referral to multiple medical specialties and multiple reviews, the diagnosis was not picked up until the patient had heavy vaginal bleeding and was admitted in tertiary center. The patient was treated eventually and recovered. Conclusion: AHA could present with buccal mucosa bleeding. It is important to remember this diagnosis when treating a chronically ill and symptomatic patient. An early diagnosis could reduce patient’s suffering and medical investigations. The treatment is possible with blood transfusion, steroids, DDAVP, activated factor VII and immunosuppressant.