Abstract
Adult-acquired Fanconi syndrome (FS) is a rare kidneycomplication of monoclonal plasma cell disorderscharacterized by dysfunction of the proximal renaltubule, resulting in metabolic changes, bone disease,and progressive renal failure. There are limited data inthe literature, mainly isolated cases reports or smallcase series.We describe our single-institution experience with 4patients diagnosed with FS associated with mono-clonal gammopathy (2 women and 2 men) fromJanuary 2001 to December 2011.The patients had a mean age of 63.5 years at diag-nosis. In 1 patient, diagnosis of monoclonal gamm-opathy and FS was simultaneous, whereas in theremaining 3 patients, FS was recognized during thefollow-up of monoclonal gammopathy.
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