Acquired aplastic anemia in children in republic of Belarus in the period after the accident at the Chernobyl nuclear power plant

Abstract

It presents the results of an epidemiological study of acquired aplastic anemia in children (0–17 years) in the Republic of Belarus for the period 1990–2015, taking into account the condition of the patient's residence area after the Chernobyl nuclear power plant accident. Тhere are 118 districts in the Republic of Belarus, from them 49 are the affected areas and 21 of this 49 are the most affected. A severe incidence rate was 0.317 ± 0.071 per 100 000 children in the areas most affected by the Chernobyl nuclear power plant accident, while in unaffected areas it was 0.217 ± 0.025 per 100 000 children (p > 0.05). The incidence of boys, regardless of the condition of the territory, was always higher than the incidence of girls living in the same territories. So a severe incidence rate of boys was 0.260 ± 0.027 per 100 000, a severe intensive incidence rate of girls – 0.187 ± 0.025 per 100 000 (p < 0.05). For the affected areas these rates were 0.304 ± 0.051 per 100 000 and 0.175 ± 0.040 per 100 000 respectively (p < 0.05). For the most affected – 0.402 ± 0.112 per 100,000 and 0.228 ± 0.086 (p > 0.05). The obtained data showed the uneven distribution of acquired aplastic anemia in the population, depending on sex and the condition of the territory. These data are planned to be taken into account in the course of further work during analysis the results of treatment.