Abstract
Acquired amegakaryocytic thrombocytopenia (AATP) is a very rare hematological disorder causing severe thrombocytopenia and bleeding. Our patient a two year old girl presented with history of severe bleeding from nose, gums, conjunctive with purpuric and petechial spots all over the body. She had mild hepatosplenomegaly with very low Platelet counts. Bone marrow examination revealed absence of apparent megakaryocytes. Bone marrow biopsy ruled out disorders of marrow suppression. This child was treated with methyl prednisolone, prednisolone and oral cyclosporine for 5 months. On follow up the child has been asymptomatic with complete improvement of the platelet counts and recovery of bone marrow picture.
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