Abstract
A number of acoustothermometrical experiments modelling hyperthermia of biological objects was carried out. After that the first preliminary acoustothermometrical measurement of laser hyperthermia of human tissues was conducted. In all experiments the changes of the thermal acoustic radiation intensity in 1.4-2.2 MHz region were controlled during both the heating and the cooling of the object (about 8-10 minutes) with the help of set of acoustothermometers. As model objects we used the beef liver and glycerin water solution in which plasticine was placed. We reconstructed the 2-D inner temperature distribution by using acoustothermometrical experimental data, i.e. we calculated position, size and temperature of thermal source. The object surface temperature was controlled with the help of IR-thermograph. Acoustothermometrical measurements were carried out during laser hyperthemia of mammary and thyroid glands for seven patients. Obtained data allowed us to estimate inner temperature changes which were a result of laser hyperthemia.
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