Abstract

The banding of red blood cells in an ultrasonic standing wave has been observed in vivo in the blood vessels of chick embryos [M. Dyson et al., Ultrasound in Medicine 1, 133 (1974)] and in whole and diluted blood in vitro [N. Baker, Nature, Lond. 239, 398 (1972)]. This banding has been attributed to forces generated by acoustic radiation pressure. If this force is balanced by the gravitational forces, the red blood cells (rbc's) will be levitated. It is interesting to note that in the absence of flow the position of levitation is independent of the size or shape of the rbc's for acoustic wavelengths large compared to rbc size and depends only on rbc density and compressibility in relation to the surrounding host medium. Therefore the position at which bands of rbc's form can be used to obtain information about their mechanical properties. We shall describe our system for levitating red blood cells (a movie will be shown), and we shall discuss how information about rbc compressibility can be deduced. [Work supported by ONR and Yale Summer Research Program.]

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