Abstract
ABSTRACT
 Background: Acute ischemic stroke is the most common cause of death after heart disease and cancer. We aimed to investigate the relationship between parameters of complete blood count in early period of ischemic stroke.
 Material Method: The study was organized as a retrospective-archive study. Patients applied Emergency Department and diagnosed as ischemic stroke were included. Demographic findings, complete blood count parameters, imaging tests, duration time in the emergency, hospitalization time were noted.
 Results: The mean age of 422 patients was 69.95 ± 12.26 years. Hypertension is the most common additional diseases, with the rate of 68.5%. While the mortality rate is 2.1% in the first 7 days, it was 5.2% in the first 30 days. The mean value of Neutrophil Lymphocyte Ratio (NLR) was significantly higher in patients who died within the first 7 days (p = 0.013). The sensitivity of NLR cut-off value, which was determined as 4.12 for death in the first 7 days, was 77.8% and specificity was 68.5%. Red Cell Distribution Width (RDW) values of patients who died within 30 days were found to be statistically significantly higher when compared to living patients. Advanced age, heart failure and atrial fibrillation were found to be significant risk factors for early mortality.
 Conclusion: In conclusion, NLR can be predictive for mortality within the first 7 days and RDW for mortality within the first 30 days. The presence of heart failure and / or atrial fibrillation and the age of 65 and above increase the risk of early mortality.
 
 Keywords: ischemic stroke, red cell distribution width, neutrophil lymphocyte ratio, early mortality
Highlights
Stroke is defined by the World Health Organization as “findings that develop rapidly and last for 24 hours or more, or may result in death, due to focal or global impairment of cerebral functions” [1]
We aimed to investigate the relationship between parameters of complete blood count in early period of ischemic stroke
In conclusion, Neutrophil Lymphocyte Ratio (NLR) can be predictive for mortality within the first 7 days and Red Cell Distribution Width (RDW) for mortality within the first 30 days
Summary
Stroke is defined by the World Health Organization as “findings that develop rapidly and last for 24 hours or more, or may result in death, due to focal or global impairment of cerebral functions” [1]. Acute stroke is the most common cause of death after cancer and heart diseases in Turkey and all over the world. Stroke is the major cause of morbidity and long-term disability in Europe. Since the mortality and morbidity rates of acute stroke are high, it is important to predict early mortality. Number of studies have been conducted with clinical findings, scoring systems, biochemical markers, and imaging methods to predict the mortality of coronary artery diseases, cancers, and strokes, which have high mortality. It was aimed to investigate the relationship between parameters of complete blood count which is an accessible, cheap, and fast test and early mortality in stroke
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