Abstract
Food was employed to elicit the vagal-antral-gastrin response which was measured by Heidenhain pouch secretion in three dogs. Direct antral stimulation by the food was avoided by making a double-mucosal diaphragm which isolated the antrum from the gastric contents without interfering with its vagal innervation. Antral pH was modified by irrigation in a series of acute stands. In the chronic portion of the experiment the innervated antrum was first isolated with an acid-secreting gastric cuff attached whereas in a succeeding preparation the antrum alone was separated from the gastric contents. In both the acute and chronic experiments changes in antral pH markedly influenced pouch secretion. It is concluded that antral pH greatly modifies gastrin output subsequent to vagal stimulation of the antrum.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
