Achieving successful pulpal anesthesia during endodontic treatment of mandibular molars: A systematic review and meta-analysis

Abstract

Background and aim: A study that show useful and secure intervention to attain pulpal anesthesia patients undergoing nonsurgical endodontic treatment for mandibular molars with symptomatic irreversible pulpitis, it is more than necessary and important, so the aim of this systematic review and meta-analysis was achieving successful pulpal anesthesia during endodontic treatment of mandibular molars. Method: MEDLINE, PubMed, Cochrane Library, Embase, ISI, google scholar were used as electronic databases to perform a systematic literature between 2015 to 2019. A commercially available software program (Endnote X9) was used for electronic title management. Searches were performed with keywords, “Endodontic”, “Endodontic treatment;”,” irreversible pulpitiss”,” pulpitiss”, “local anesthetics” “Pulpal”,“Anesthesia Strategies”, “Anesthesia”, “Mandibular Molar”,” Symptomatic Irreversible Pulpitis”. Result: A total of 151 potentially relevant titles and abstracts were found during the electronic and manual search. Finally, a total of 13 publications fulfilled the inclusion criteria required for this systematic review. Comparing intervention groups with each other using 2 lidocaine with 1:100,000 epinephrine was the least effective intervention to achieve pulpal anesthesia 1.095 (95 CI: 1.046 – 1.147) with Heterogeneity found (I2 = 28.79; P = 0.000). Conclusion: Using 2 lidocaine with 1:100,000 epinephrine was the least effective intervention to achieve pulpal anesthesia. © 2020, Advanced Scientific Research. All rights reserved.