Abstract
Vaccine therapy as a method of immunotherapy is a promising direction in neurooncology, the ultimate goal of which is to increase the effectiveness of the treatment of patients with malignant glial tumors of the brain. In this article, based on the analysis of domestic and foreign literature sources devoted to the creation and application of vaccine therapy in neurooncology, the main principles of vaccine therapy used in the treatment of glioblastomas are considered, and the results of the most significant clinical studies in this area are presented. The article discusses the prospects for the use of vaccine therapy as an additional treatment for glioblastoma and possible obstacles to its widespread use.
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